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Designed to replace the 375 Weatherby Magnum, deep penetration and bone smashing power are the calling cards of the 378. Its massive case holds so much powder that Federal designed its super-hot 215 primer to handle the load. Roy Weatherby’s 378 delivers 34 percent more energy at the muzzle than the powerful 375 H&H Magnum. Since 1955, the 378 has become one of the world’s most popular cartridges for the largest of big game animals.
| Bullet Type | Bullet Weight | B/C | @Muzzle | 100 yds | 200 yds | 300 yds | 400 yds | 500 yds |
|---|---|---|---|---|---|---|---|---|
| Hornady® Interlock® | 270 | .380 | 3180 | 2921 | 2677 | 2445 | 2225 | 2017 |
| Barnes® TSX™ | 270 | .326 | 3060 | 2868 | 2684 | 2507 | 2337 | 2174 |
| Hornady® DGXB® | 300 | .250 | 2925 | 2558 | 2220 | 1908 | 1627 | 1383 |
| Hornady® DGS® | 300 | .275 | 2925 | 2591 | 2280 | 1991 | 1725 | 1489 |
| Bullet Type | Bullet Weight | B/C | @Muzzle | 100 yds | 200 yds | 300 yds | 400 yds | 500 yds |
|---|---|---|---|---|---|---|---|---|
| Hornady® Interlock® | 270 | .380 | 6062 | 5115 | 4295 | 3583 | 2968 | 2438 |
| Barnes® TSX™ | 270 | .326 | 5615 | 4932 | 4319 | 3770 | 3276 | 2834 |
| Hornady® DGXB® | 300 | .250 | 5699 | 4360 | 3283 | 2424 | 1764 | 1274 |
| Hornady® DGS® | 300 | .275 | 5699 | 4470 | 3461 | 2640 | 1983 | 1476 |
| Bullet Type | Bullet Weight | B/C | 100 yds | 200 yds | 300 yds | 400 yds | 500 yds |
|---|---|---|---|---|---|---|---|
| Hornady® Interlock® | 270 | .380 | 1.3 | 0.0 | -6.1 | -18.1 | -37.1 |
| Barnes® TSX™ | 270 | .326 | 1.3 | 0.0 | -6.2 | -17.9 | -36.1 |
| Hornady® DGXB® | 300 | .250 | 1.9 | 0.0 | -9.0 | -27.8 | -60.0 |
| Hornady® DGS® | 300 | .275 | 1.8 | 0.0 | -8.6 | -26.1 | -55.4 |
Norbert –
It is the “what ever walks on this planet” cartridge……
dråparn –
10+ moose roebuck and beaver have felt the power of the 378. My favorite rifle
Tom –
One shot kills when hunting boar is guaranteed. Exit holes like the bottom of a beer stud.
If you want just to “plink” around, 0,5″ groups of 3 shots at 100 yards are not uncommon if you do reloading with Barnes TSX bullets.
Jesse –
As a long range caliber it’s hard to beat the 378 weatherby ..
I use this rifle ( many times ) on African plains game out way past 500 yards with a high bc 300 gr bullet …
This is my ultimate hunting experience ever !!
Regards Jesse Wiehahn
Nick –
A fine weapon to take down huge bull moose, but not so much the little whitetails my crazy American neighbor shoots with it! I think the bullet field dresses whatever is left of it!
Sawman –
When Life is on the line.
378 WEATHERBY MAGNUM
Trust no other.
johnny dawson –
Hand-load results: three shots under a quarter at a hundred yards with the Sierra 300 grain boat tail.
Jesse Wiehahn –
African game are extremely tough to go down .. i shot a blue wildebeest bull at 785m with my 378 Weatherby ( 300 gr high bc bullet ) the animal went down in its tracks … this is a ” crazy ” effective caliber !!!!!
Massimiliano –
Simply the best big game cartridge ever made. The 378 Wby has the punch of a 500 NE and the trajectory of a 300 Win mag.
Shawn (verified owner) –
The 378 Wby is my ALL-Time favorite, from Pennsylvania big game hunting to Kodiak for Big Brownies, there is no comparison. I have retired my 300 Winch Mag and 375 H&H, for there is No-Need for them!